Minneapolis (MSP) to Knoxville (TYS) Flight Schedule

Flight Minneapolis(MSP) to Knoxville(TYS)
CHANGE DIRECTION

Minneapolis-Saint Paul International Airport McGhee Tyson Airport
MSP : Minneapolis , United States TYS : Knoxville , United States
UTC-5(DST) UTC-4(DST)

Minneapolis to Knoxville Flight Schedule(September 2025)

Flight from Minneapolis(MSP) to Knoxville(TYS) is operated by 1 airline : Delta Air Lines (DL). You can check flight schedules, flight duration, and aircraft types.

Change Direction(TYS to MSP)

Minneapolis (MSP) to Knoxville (TYS) Flight Schedule

LastUpdate : 2025/09/01 06:00

Flight Schedule on September 2025 , Direct flight departure from Minneapolis with all airlines , flight number, flight duration, aircraft type.

September 2025
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Flight Number / Airline Departure Time Arrival Time Flight Duration Operating Days Aircraft Type Airfare / Tickets
DL5335
Delta Air Lines
13:11 16:24 2h13m
MTW---S (Sep 1, Sep 7–10)
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13:15 16:23 2h8m
M--TF-S (Sep 11–12, Sep 14–15, Sep 18–19, Sep 21–22, Sep 25–26, Sep 28–29)
CRJ-900
Codeshare flight
DL5527
Delta Air Lines
20:39 23:55 2h16m
MTWTF-S (Sep 1–5, Sep 7)
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19:15 22:27 2h12m
-----S- (Sep 6)
CRJ-900
20:39 23:55 2h16m
MTW---- (Sep 8–10)
CRJ-900
20:20 23:36 2h16m
---TF-S (Sep 11–12, Sep 14)
CRJ-900
19:24 22:35 2h11m
-----S- (Sep 13, Sep 20, Sep 27)
CRJ-900
20:20 23:36 2h16m
MTWTF-S (Sep 15–19, Sep 21–26, Sep 28–30)
CRJ-900
Codeshare flight
Change Direction(TYS to MSP)
Flight schedules as of September 01, 2025, 06:00 AM(OAG data). Schedules may change without notice, so please check with airlines before booking. Refer to FlyTeam's terms of use before proceeding. Some airlines and flight numbers may not be displayed.

FAQ : Minneapolis to Knoxville

How many airlines fly from Minneapolis to Knoxville ?
As of September 2025, 1 airline operate direct flights from Minneapolis (MSP) to Knoxville (TYS) : Delta Air Lines.
How far is it from Minneapolis to Knoxville?
The distance between Minneapolis (MSP) to Knoxville (TYS) is approximately 790 miles(1,270km) by air.
What is the time difference between Minneapolis to Knoxville?
The time difference between Minneapolis-Saint Paul International Airport(Minneapolis) and McGhee Tyson Airport(Knoxville) is +1 hour. Knoxville is 1 hour ahead of Minneapolis.Minneapolis is currently observing daylight saving time (DST) from March 9, 2025 to November 2, 2025.Knoxville is currently observing daylight saving time (DST) from March 9, 2025 to November 2, 2025.