Chicago (ORD) to Knoxville (TYS) Flight Schedule

Flight Chicago(ORD) to Knoxville(TYS)
CHANGE DIRECTION

O'Hare International Airport McGhee Tyson Airport
ORD : Chicago , United States TYS : Knoxville , United States
UTC-5(DST) UTC-4(DST)

Chicago to Knoxville Flight Schedule(September 2025)

Flight from Chicago(ORD) to Knoxville(TYS) is operated by 2 airlines : United Airlines (UA),American Airlines (AA). You can check flight schedules, flight duration, and aircraft types.

Change Direction(TYS to ORD)

Chicago (ORD) to Knoxville (TYS) Flight Schedule

LastUpdate : 2025/09/01 06:00

Flight Schedule on September 2025 , Direct flight departure from Chicago with all airlines , flight number, flight duration, aircraft type.

September 2025
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  • American Airlines [ Show / Hide ]
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Change Direction(TYS to ORD)
Flight Number / Airline Departure Time Arrival Time Flight Duration Operating Days Aircraft Type Airfare / Tickets
UA5726
United Airlines
07:18 10:13 1h55m
M--TF-S (Sep 1, Sep 4–5, Sep 7, Sep 15, Sep 18–19, Sep 21–22)
E175 (WL) Trip.com PRICES HIS Prices Expedia PRICES skyticket PRICES
07:15 10:10 1h55m
MT-TFSS (Sep 25–30)
E175 (WL)
Codeshare flight
UA335
United Airlines
07:17 09:58 1h41m
-----S- (Sep 6, Sep 13, Sep 20)
A319 Trip.com PRICES HIS Prices Expedia PRICES skyticket PRICES
Codeshare flight
UA4393
United Airlines
07:18 10:11 1h53m
-TW---- (Sep 2–3, Sep 9–10, Sep 16–17, Sep 23–24)
CRJ-550 (Op. G7) Trip.com PRICES HIS Prices Expedia PRICES skyticket PRICES
Codeshare flight
UA3520
United Airlines
07:22 10:13 1h51m
M------ (Sep 8)
E175 (WL) Trip.com PRICES HIS Prices Expedia PRICES skyticket PRICES
Codeshare flight
AA5202
American Airlines
09:28 12:21 1h53m
----F-- (Sep 5)
CRJ-700 Trip.com PRICES HIS Prices Expedia PRICES skyticket PRICES
11:48 14:33 1h45m
-----S- (Sep 6, Sep 13)
CRJ-700
09:28 12:21 1h53m
M-WTF-S (Sep 7–8, Sep 10–12, Sep 14–15, Sep 17–19, Sep 21–22, Sep 24–26, Sep 28)
CRJ-700
11:48 14:33 1h45m
-----S- (Sep 20, Sep 27)
CRJ-700
09:28 12:21 1h53m
M------ (Sep 29)
CRJ-700
Codeshare flight
AA5140
American Airlines
09:40 12:26 1h46m
MT----- (Sep 1–2)
CRJ-700 Trip.com PRICES HIS Prices Expedia PRICES skyticket PRICES
Codeshare flight
UA4194
United Airlines
10:35 13:25 1h50m
Daily (Sep 1–12, Sep 14–19, Sep 21–30)
CRJ-550 (Op. G7) Trip.com PRICES HIS Prices Expedia PRICES skyticket PRICES
Codeshare flight
UA5318
United Airlines
10:35 13:25 1h50m
-----S- (Sep 13, Sep 20)
CRJ-550 Trip.com PRICES HIS Prices Expedia PRICES skyticket PRICES
Codeshare flight
AA3361
American Airlines
11:53 14:34 1h41m
M------ (Sep 1)
E170 Trip.com PRICES HIS Prices Expedia PRICES skyticket PRICES
Codeshare flight
AA4537
American Airlines
11:56 14:43 1h47m
M--TF-S (Sep 5, Sep 7–8, Sep 11–12, Sep 14–15, Sep 18–19, Sep 21–22, Sep 25–26, Sep 28–29)
E175 Trip.com PRICES HIS Prices Expedia PRICES skyticket PRICES
11:59 14:46 1h47m
-T----- (Sep 9, Sep 16, Sep 23, Sep 30)
E175
12:20 15:06 1h46m
--W---- (Sep 10, Sep 17, Sep 24)
E175
AA3409
American Airlines
13:37 16:19 1h42m
Daily (Sep 3, Sep 6–30)
E170 Trip.com PRICES HIS Prices Expedia PRICES skyticket PRICES
Codeshare flight
AA5378
American Airlines
13:55 16:36 1h41m
MT----- (Sep 1–2)
CRJ-700 Trip.com PRICES HIS Prices Expedia PRICES skyticket PRICES
Codeshare flight
UA5399
United Airlines
14:10 17:00 1h50m
Daily (Sep 1–24)
CRJ-550 Trip.com PRICES HIS Prices Expedia PRICES skyticket PRICES
14:28 17:18 1h50m
MT-TFSS (Sep 25–30)
CRJ-550
Codeshare flight
AA5195
American Airlines
18:14 21:00 1h46m
Daily (Sep 3–30)
CRJ-700 Trip.com PRICES HIS Prices Expedia PRICES skyticket PRICES
Codeshare flight
AA5207
American Airlines
18:29 21:13 1h44m
MT----- (Sep 1–2)
CRJ-700 Trip.com PRICES HIS Prices Expedia PRICES skyticket PRICES
Codeshare flight
UA2005
United Airlines
19:55 22:45 1h50m
MTWT-SS (Sep 1–4, Sep 6–11, Sep 13–18, Sep 20–21)
737-700 Trip.com PRICES HIS Prices Expedia PRICES skyticket PRICES
19:45 22:36 1h51m
----F-- (Sep 5, Sep 12, Sep 19)
A319
19:55 22:45 1h50m
MTW---- (Sep 22–24)
737-700
20:00 22:50 1h50m
MT-TFSS (Sep 25–30)
737-700
Codeshare flight
Change Direction(TYS to ORD)
Flight schedules as of September 01, 2025, 06:00 AM(OAG data). Schedules may change without notice, so please check with airlines before booking. Refer to FlyTeam's terms of use before proceeding. Some airlines and flight numbers may not be displayed.

FAQ : Chicago to Knoxville

How many airlines fly from Chicago to Knoxville ?
As of September 2025, 2 airlines operate direct flights from Chicago (ORD) to Knoxville (TYS) : United Airlines , American Airlines.
How far is it from Chicago to Knoxville?
The distance between Chicago (ORD) to Knoxville (TYS) is approximately 480 miles(760km) by air.
What is the time difference between Chicago to Knoxville?
The time difference between O'Hare International Airport(Chicago) and McGhee Tyson Airport(Knoxville) is +1 hour. Knoxville is 1 hour ahead of Chicago.Chicago is currently observing daylight saving time (DST) from March 9, 2025 to November 2, 2025.Knoxville is currently observing daylight saving time (DST) from March 9, 2025 to November 2, 2025.